Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12630
Abstract: Nuclear factor of activated T cells 5 (NFAT5) is a transcription factor involved in the regulation of several genes involved in the response to extracellular hyperosmolality. Recently, the uptake of ibuprofen by an as yet… read more here.
Keywords: mdck cells; nfat5 involved; regulation; ibuprofen ... See more keywords
Association of regular paracetamol or ibuprofen usage with the risk of incident kidney stones.
Sign Up to like & getrecommendations! Published in 2025 at "British journal of clinical pharmacology"
DOI: 10.1002/bcp.70342
Abstract: OBJECTIVE Kidney stones affect approximately 10% of adults globally, with increasing prevalence and significant associated morbidity. While ibuprofen and paracetamol are widely used over-the-counter analgesics, their associations with kidney stone risk remain unclear. This study… read more here.
Keywords: usage; ibuprofen; risk; kidney stones ... See more keywords
Chiral bioanalytical methods in bioequivalence studies of intravenous vs. oral formulations of ibuprofen.
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DOI: 10.1002/chir.23258
Abstract: According to the Ibuprofen Product-Specific Bioequivalence Guidance of the European Medicines Agency, achiral bioanalytical methods are considered acceptable for demonstration of bioequivalence of ibuprofen-containing products. The aim of this investigation is to compare the bioequivalence… read more here.
Keywords: bioequivalence; sum enantiomers; ibuprofen; bioanalytical methods ... See more keywords
Enantioselective separation and determination of ibuprofen: Stereoselective pharmacokinetics, pharmacodynamics and analytical methods.
Sign Up to like & getrecommendations! Published in 2024 at "Chirality"
DOI: 10.1002/chir.23647
Abstract: Ibuprofen (IBP), the 29th most prescribed drug in the United States in 2019, is a widely used nonsteroidal anti-inflammatory drug (NSAID) comprising two enantiomers, (R)-IBP and (S)-IBP, collectively known as (RS)-IBP. This critical review examines… read more here.
Keywords: separation determination; ibuprofen; pharmacology; enantioselective separation ... See more keywords
Smartphone‐based colorimetric chiral recognition of ibuprofen using aptamers‐capped gold nanoparticles
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DOI: 10.1002/elps.201700372
Abstract: Sensitive and fast detection of ibuprofen enantiomers is very critical for required routine monitoring and risk assessment of trace pollutants in water samples. Here a simple, rapid and highly sensitive android smartphone application for chiral… read more here.
Keywords: detection; gold nanoparticles; capped gold; ibuprofen ... See more keywords
Combined Biological Effects of N-Bromotaurine Analogs and Ibuprofen. Part I: Influence on Inflammatory Properties of Macrophages.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_84
Abstract: Taurine haloamines (N-chlorotaurine, N-bromotaurine) due to their strong antiseptic and anti-inflammatory properties are good candidates for topical application in treatment of skin inflammatory/infectious disorders. Recently, we have demonstrated that more stable N-bromotaurine analogs (N-dibromo-dimethyl taurine,… read more here.
Keywords: anti inflammatory; ibuprofen; bromotaurine analogs; combined biological ... See more keywords
Alginate-chitosan/MWCNTs nanocomposite: a novel approach for sustained release of Ibuprofen
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Polymer Research"
DOI: 10.1007/s10965-020-02342-8
Abstract: The use of alginate as excipient in dosage formulation is a common trend due to mild gelling ability, biocompatibility, biodegradability, non-toxicity, and mucoadhesive properties. However, these formulations possess major disadvantages, such as rapid hydration, burst… read more here.
Keywords: alginate chitosan; mwcnts nanocomposite; ibuprofen; chitosan mwcnts ... See more keywords
Combined 1-Deoxynojirimycin and Ibuprofen Treatment Decreases Microglial Activation, Phagocytosis and Dopaminergic Degeneration in MPTP-Treated Mice
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroimmune Pharmacology"
DOI: 10.1007/s11481-020-09925-8
Abstract: Inflammation is a predominant aspect of neurodegenerative diseases and experimental studies performed in animal models of Parkinson’s disease (PD) suggesting that a sustained neuroinflammation exacerbates the nigrostriatal degeneration pathway. The central role of microglia in… read more here.
Keywords: treatment; microglial activation; mptp treated; ibuprofen ... See more keywords
Working Towards an Appropriate Use of Ibuprofen in Children: An Evidence-Based Appraisal
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DOI: 10.1007/s40265-017-0751-z
Abstract: Ibuprofen is the most widely used non-steroidal anti-inflammatory drug (NSAID) for the treatment of inflammation, mild-to-moderate pain and fever in children, and is the only NSAID approved for use in children aged ≥3 months. Its efficacy… read more here.
Keywords: use; ibuprofen; working towards; drug ... See more keywords
Anti-Sporothrix activity of ibuprofen combined with antifungal
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Microbiology"
DOI: 10.1007/s42770-020-00327-9
Abstract: The in vitro activity of ibuprofen, a nonsteroidal anti-inflammatory drug, was evaluated against Sporothrix brasiliensis and S. schenckii , either alone or in combination with amphotericin B, itraconazole, or terbinafine. The inhibitory activity of ibuprofen… read more here.
Keywords: combination; activity ibuprofen; ibuprofen; amphotericin itraconazole ... See more keywords
The effects of intra-articular injection of ibuprofen on knee joint cartilage and synovium in rats
Sign Up to like & getrecommendations! Published in 2019 at "Acta Orthopaedica et Traumatologica Turcica"
DOI: 10.1016/j.aott.2019.03.013
Abstract: Objective The aim of this animal study was to investigate the short and long-term local histomorphologic effects and the utility of intra-articular application of ibuprofen. Methods Forty-six Wistar Albino rats were used in the study.… read more here.
Keywords: ibuprofen; ibuprofen injected; knee joint; inflammation ... See more keywords