State-dependent block of voltage-gated sodium channels by the casein-kinase 1 inhibitor IC261
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DOI: 10.1007/s10637-017-0429-0
Abstract: SummaryBackground and Purpose IC261 (3-[(2,4,6-trimethoxyphenyl)methylidenyl]-indolin-2-one) has previously been introduced as an isoform specific inhibitor of casein kinase 1 (CK1) causing cell cycle arrest or cell death of established tumor cell lines. However, it is reasonable… read more here.
Keywords: state; ic261; sodium; gated sodium ... See more keywords