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Synthesis, computational studies and biological evaluation of new 1-acetyl-3-aryl thiourea derivatives as potent cholinesterase inhibitors

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Published in 2017 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-017-1829-6

Abstract: A new series of 1-acetyl-3-aryl thioureas (3f1–15) was synthesized by the reaction of acetyl isothiocyanate with a variety of suitably substituted aromatic anilines. The acetyl isothiocyanate was freshly prepared by reaction of corresonding acid chloride… read more here.

Keywords: inhibitor; acetyl; acetylcholinesterase; acetyl aryl ... See more keywords