ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-25189-z
Abstract: Circulating tumor cell (CTC) clusters mediate metastasis at a higher efficiency and are associated with lower overall survival in breast cancer compared to single cells. Combining single-cell RNA sequencing and protein analyses, here we report… read more here.
Keywords: breast cancer; metastasis; tumor cell; icam1 ... See more keywords
ICAM1 promotes bone metastasis via integrin‐mediated TGF‐β/EMT signaling in triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15532
Abstract: Bone‐related events caused by breast cancer bone metastasis substantially compromise the survival and quality of life of patients. Because triple‐negative breast cancer (TNBC) lacks hormone receptors and Her2‐targeted therapeutic options, progress in the treatment of… read more here.
Keywords: metastasis; breast cancer; icam1; bone metastasis ... See more keywords
Macrophage secretory IL-1β promotes docetaxel resistance in head and neck squamous carcinoma via SOD2/CAT-ICAM1 signaling
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.157285
Abstract: Docetaxel (DTX) combined with cisplatin and 5-fluorouracil has been used as induction chemotherapy for head and neck squamous cell carcinoma (HNSCC). However, the development of acquired resistance remains a major obstacle to treatment response. Tumor-associated… read more here.
Keywords: head neck; resistance; neck squamous; icam1 ... See more keywords
ICAM1-Targeting Theranostic Nanoparticles for Magnetic Resonance Imaging and Therapy of Triple-Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s374293
Abstract: Purpose Owing to the lack of effective biomarkers, triple-negative breast cancer (TNBC) has the worst prognosis among all subtypes of breast cancer. Meanwhile, tremendous progress has been made to identify biomarkers for TNBC. However, limited… read more here.
Keywords: nanoparticle; triple negative; breast cancer; icam1 ... See more keywords
ID3 mediates BMP2-induced downregulation of ICAM1 expression in human endometiral stromal cells and decidual cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1090593
Abstract: Recurrent pregnancy loss (RPL) remains an unsolved problem in obstetrics and gynecology, and up to 50% of RPL cases are unexplained. Unexplained RPL (uRPL) is widely considered to be related to an aberrant endometrial microenvironment.… read more here.
Keywords: icam1 expression; downregulation icam1; unexplained rpl; icam1 ... See more keywords
Construction of a Vero Cell Line Expressing Human ICAM1 for the Development of Rhinovirus Vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14102235
Abstract: Human rhinoviruses (HRVs) are small non-enveloped RNA viruses that belong to the Enterovirus genus within the Picornaviridae family and are known for causing the common cold. Though symptoms are generally mild in healthy individuals, the… read more here.
Keywords: vero cell; development; vero cells; vero ... See more keywords