A Novel 167‐Amino Acid Protein Encoded by CircPCSK6 Inhibits Intrahepatic Cholangiocarcinoma Progression via IKBα Ubiquitination
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202409173
Abstract: Intrahepatic cholangiocarcinoma (ICC), a formidable challenge in oncology, demands innovative biomarkers and therapeutic targets. This research highlights the importance of the circular RNA (circRNA) circPCSK6 and its peptide derivative circPCSK6‐167aa in ICC. CircPCSK6 is significantly… read more here.
Keywords: circpcsk6; ubiquitination; intrahepatic cholangiocarcinoma; circpcsk6 167aa ... See more keywords
Intraclass correlation: Improved modeling approaches and applications for neuroimaging
Sign Up to like & getrecommendations! Published in 2018 at "Human Brain Mapping"
DOI: 10.1002/hbm.23909
Abstract: Intraclass correlation (ICC) is a reliability metric that gauges similarity when, for example, entities are measured under similar, or even the same, well‐controlled conditions, which in MRI applications include runs/sessions, twins, parent/child, scanners, sites, and… read more here.
Keywords: modeling approaches; intraclass correlation; icc; mixed effects ... See more keywords
Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF‐β1 /P‐smad3 signaling through HIF‐1a
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23687
Abstract: Intrahepatic cholangiocarcinoma (ICC) is a high‐grade malignant digestive system tumor with an insidious onset and unfavorable prognosis. Liensinine, a small molecule derived from plants, has been proven to have significant tumor suppressor activity in other… read more here.
Keywords: smad3 signaling; intrahepatic cholangiocarcinoma; icc; liensinine ... See more keywords
Zinc Finger Protein 263 Augments Autophagy and Promotes Intrahepatic Cholangiocarcinoma Proliferation
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23847
Abstract: Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer characterized by a poor prognosis. Despite Zinc finger proteins (ZNFs) importance in tumor development and progression, it is unknown how dysregulated ZNF263 contributes to intrahepatic cholangiocarcinoma. This study… read more here.
Keywords: zinc finger; znf263; intrahepatic cholangiocarcinoma; cholangiocarcinoma ... See more keywords
Feasibility Study for Dual Phase Free Breathing 3D bSSFP MRA With Preserved Eddy-Current Tolerance With Adaptive k-Space Lengths (PETAL) Acquisition.
Sign Up to like & getrecommendations! Published in 2025 at "Magnetic resonance in medicine"
DOI: 10.1002/mrm.70192
Abstract: PURPOSE To demonstrate the feasibility of a novel dual-phase self-navigated, free-breathing balanced steady-state free-precession whole-heart MRA acquisition for aortic annulus size measurement using a Cartesian trajectory that mitigates eddy-current artifacts by minimizing k-space jumps between… read more here.
Keywords: eddy current; free breathing; acquisition; icc ... See more keywords
Validation of the 25 level modified shuttle test in children with cystic fibrosis.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric pulmonology"
DOI: 10.1002/ppul.26452
Abstract: OBJECTIVE To evaluate the validity and reliability of the modified shuttle 25-level test (MST-25) in children with cystic fibrosis (CF). METHODS A prospective single center study in clinically stable children with CF. Participants undertook two… read more here.
Keywords: cpet; reliability; test; icc ... See more keywords
Two-Dimensional Strain is more Precise than Conventional Measures of Left Ventricular Systolic Function in Pediatric Patients
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Cardiology"
DOI: 10.1007/s00246-019-02243-8
Abstract: Ejection fraction (EF) and fractional shortening (FS) are standard methods of quantifying left ventricular (LV) systolic function. 2D global longitudinal strain (2D GLS) is a well-established, but underutilized method for LV function quantification. The aim… read more here.
Keywords: loa icc; systolic function; gls; bias loa ... See more keywords
Intrahepatic cholangiocarcinoma: MRI texture signature as predictive biomarkers of immunophenotyping and survival
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-07524-y
Abstract: Clinical evidence suggests that the response to immune checkpoint blockade depends on the immune status in the tumor microenvironment. This study aims to predict the immunophenotyping (IP) and overall survival (OS) of intrahepatic cholangiocarcinoma (ICC)… read more here.
Keywords: texture signature; feature; icc; icc patients ... See more keywords
Invasion category-oriented lymph node metastases of cholangiocarcinoma and the prognostic impact
Sign Up to like & getrecommendations! Published in 2020 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-020-01955-3
Abstract: It was speculated that intrahepatic cholangiocarcinoma (ICC) invasion would influence cancer progression, such as lymph node (LN) metastasis, and the efficacy of LN dissection (LND). The purpose of this study is to evaluate the LN… read more here.
Keywords: invasion; icc; type; lymph node ... See more keywords
Reproducibility and reliability of retinal and optic disc measurements obtained with swept-source optical coherence tomography in a healthy population
Sign Up to like & getrecommendations! Published in 2018 at "Japanese Journal of Ophthalmology"
DOI: 10.1007/s10384-018-00647-2
Abstract: PurposeTo analyze the reproducibility of macular and peripapillary thickness measurements, and optic nerve morphometric data obtained with Triton Optical coherence tomography (OCT) in a healthy population.Study designObservational cross sectional study.Material and methodsA total of 108… read more here.
Keywords: optical coherence; reproducibility; icc; cov ... See more keywords
Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Current Medical Science"
DOI: 10.1007/s11596-019-2125-0
Abstract: The molecular mechanisms underlying the development of intrahepatic cholangiocarcinoma (ICC) are not clear yet. In this study, we investigated the involvement of Notch1 in the development of ICC. The cDNA microarray analysis showed that Notch1… read more here.
Keywords: intrahepatic cholangiocarcinoma; formation proliferation; formation; icc ... See more keywords