NOTCH-YAP1/TEAD-DNMT1 axis drives hepatocyte reprogramming into intrahepatic cholangiocarcinoma.
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DOI: 10.1053/j.gastro.2022.05.007
Abstract: BACKGROUND AND AIM Intrahepatic cholangiocarcinoma (ICC) is a devastating liver cancer with extremely high intra- and inter-tumoral molecular heterogeneity, partly due to its diverse cellular origins. We investigated clinical relevance and the molecular mechanisms underlying… read more here.
Keywords: yap1 tead; dnmt1; yap1; icc development ... See more keywords