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   Articles with "icer" as a keyword



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Anticoagulant plus antiplatelet therapy for atrial fibrillation

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recommendations! Published in 2018 at "Herz"

DOI: 10.1007/s00059-018-4747-6

Abstract: BackgroundEmerging evidence indicates combination therapy with anticoagulants and antiplatelet agents for atrial fibrillation (AF) will be increasingly required. Numerous studies compare the efficacy and cost-effectiveness of anticoagulation alone in AF, i. e., non-vitamin K oral anticoagulants (NOACs)… read more here.

Keywords: die; icer; warfarin; der ... See more keywords
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Is the Choice of Cost-Effectiveness Threshold in Cost-Utility Analysis Endogenous to the Resulting Value of Technology? A Systematic Review

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recommendations! Published in 2020 at "Applied Health Economics and Health Policy"

DOI: 10.1007/s40258-020-00606-4

Abstract: Cost-utility analysis (CUA) is widely used for health technology assessment; however, concerns exist that cost-utility analysts may suggest higher cost-effectiveness thresholds (CETs) to compensate for technologies of relatively lower value. We explored whether selection of… read more here.

Keywords: icer; analysis; cost; value ... See more keywords
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PDE4 and mAKAP&bgr; are nodal organizers of &bgr;2-ARs nuclear PKA signalling in cardiac myocytes

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recommendations! Published in 2018 at "Cardiovascular Research"

DOI: 10.1093/cvr/cvy110

Abstract: Aims β1- and β2-adrenergic receptors (β-ARs) produce different acute contractile effects on the heart partly because they impact on different cytosolic pools of cAMP-dependent protein kinase (PKA). They also exert different effects on gene expression… read more here.

Keywords: pka activation; icer; stimulation; pka ... See more keywords
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Differential Expression of CREM/ICER Isoforms Is Associated with the Spontaneous Control of HIV Infection

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recommendations! Published in 2022 at "mBio"

DOI: 10.1128/mbio.01979-21

Abstract: A small group of HIV-infected individuals, termed elite controllers (ECs), display control of HIV replication in the absence of antiretroviral therapy (ART). However, the mechanism of ECs’ resistance to HIV replication is not clear. ABSTRACT… read more here.

Keywords: hiv; icer; control hiv; hiv replication ... See more keywords
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Measuring the Value of New Drugs: Validity and Reliability of 4 Value Assessment Frameworks in the Oncology Setting.

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recommendations! Published in 2017 at "Journal of managed care & specialty pharmacy"

DOI: 10.18553/jmcp.2017.23.6-a.s34

Abstract: BACKGROUND Several organizations have developed frameworks to systematically assess the value of new drugs. OBJECTIVE To evaluate the convergent validity and interrater reliability of 4 value frameworks to understand the extent to which these tools… read more here.

Keywords: cancer drugs; asco esmo; icer; value ... See more keywords