LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "icer" as a keyword



Anticoagulant plus antiplatelet therapy for atrial fibrillation

Sign Up to like & get
recommendations! Published in 2018 at "Herz"

DOI: 10.1007/s00059-018-4747-6

Abstract: BackgroundEmerging evidence indicates combination therapy with anticoagulants and antiplatelet agents for atrial fibrillation (AF) will be increasingly required. Numerous studies compare the efficacy and cost-effectiveness of anticoagulation alone in AF, i. e., non-vitamin K oral anticoagulants (NOACs)… read more here.

Keywords: die; icer; warfarin; der ... See more keywords
Photo by dawson2406 from unsplash

Is the Choice of Cost-Effectiveness Threshold in Cost-Utility Analysis Endogenous to the Resulting Value of Technology? A Systematic Review

Sign Up to like & get
recommendations! Published in 2020 at "Applied Health Economics and Health Policy"

DOI: 10.1007/s40258-020-00606-4

Abstract: Cost-utility analysis (CUA) is widely used for health technology assessment; however, concerns exist that cost-utility analysts may suggest higher cost-effectiveness thresholds (CETs) to compensate for technologies of relatively lower value. We explored whether selection of… read more here.

Keywords: icer; analysis; cost; value ... See more keywords

Inflation-adjusted analysis of ICER’s Unsupported Price Increase reports: contextualizing drug spending changes

Sign Up to like & get
recommendations! Published in 2024 at "Journal of Medical Economics"

DOI: 10.1080/13696998.2024.2428109

Abstract: Abstract Objective The Institute for Clinical and Economic Review (ICER) publishes annual Unsupported Price Increase (UPI) reports on prescription drugs, which have gained attention from policymakers and healthcare stakeholders. These reports do not adjust for… read more here.

Keywords: unsupported price; spending; inflation; price ... See more keywords

PDE4 and mAKAP&bgr; are nodal organizers of &bgr;2-ARs nuclear PKA signalling in cardiac myocytes

Sign Up to like & get
recommendations! Published in 2018 at "Cardiovascular Research"

DOI: 10.1093/cvr/cvy110

Abstract: Aims β1- and β2-adrenergic receptors (β-ARs) produce different acute contractile effects on the heart partly because they impact on different cytosolic pools of cAMP-dependent protein kinase (PKA). They also exert different effects on gene expression… read more here.

Keywords: pka activation; icer; stimulation; pka ... See more keywords

Phosphorylation deficient inducible cAMP early repressor (ICER) modulates tumorigenesis and survival in a transgenic zebrafish (Danio rerio) model of melanoma

Sign Up to like & get
recommendations! Published in 2025 at "Biology Open"

DOI: 10.1101/2025.02.21.639575

Abstract: Melanoma, the most lethal form of skin cancer, is commonly associated by mutations in the BRAF gene, particularly BRAFV600E, which drives tumor proliferation via ERK1/2 signaling cascade. While BRAF inhibitors initially demonstrate efficacy, therapeutic resistance… read more here.

Keywords: camp early; melanoma; icer; inducible camp ... See more keywords

Differential Expression of CREM/ICER Isoforms Is Associated with the Spontaneous Control of HIV Infection

Sign Up to like & get
recommendations! Published in 2022 at "mBio"

DOI: 10.1128/mbio.01979-21

Abstract: A small group of HIV-infected individuals, termed elite controllers (ECs), display control of HIV replication in the absence of antiretroviral therapy (ART). However, the mechanism of ECs’ resistance to HIV replication is not clear. ABSTRACT… read more here.

Keywords: hiv; icer; control hiv; hiv replication ... See more keywords

Measuring the Value of New Drugs: Validity and Reliability of 4 Value Assessment Frameworks in the Oncology Setting.

Sign Up to like & get
recommendations! Published in 2017 at "Journal of managed care & specialty pharmacy"

DOI: 10.18553/jmcp.2017.23.6-a.s34

Abstract: BACKGROUND Several organizations have developed frameworks to systematically assess the value of new drugs. OBJECTIVE To evaluate the convergent validity and interrater reliability of 4 value frameworks to understand the extent to which these tools… read more here.

Keywords: cancer drugs; asco esmo; icer; value ... See more keywords

Cost-effectiveness of atezolizumab plus chemotherapy for advanced/recurrent endometrial cancer

Sign Up to like & get
recommendations! Published in 2024 at "Journal of Gynecologic Oncology"

DOI: 10.3802/jgo.2024.35.e83

Abstract: Objective This study assessed the cost-effectiveness of atezolizumab in combination with chemotherapy for patients with advanced or recurrent endometrial cancer (EC) from the U.S. payer’s perspective. Methods A cost-effectiveness study was conducted using a Markov… read more here.

Keywords: chemotherapy; advanced recurrent; cost; icer ... See more keywords