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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2886
Abstract: Background: Recent evidence have indicated several tumor-intrinsic oncogene pathways in T cell exclusion and immune evasion of cancers . In hepatocellular carcinoma (HCC), Wnt/β-catenin (CTNNB1) signaling activation is highly prevalent and has been reported to…
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Keywords:
wnt catenin;
hcc;
icg 001;
ctnnb1 ... See more keywords
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Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.pedca19-b26
Abstract: Osteosarcoma is the most common malignant bone tumor in the pediatric population, representing around 4 cases per million people per year in the world. Patient survival is closely related to the response of tumor cells…
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Keywords:
catenin cbp;
catenin;
osteosarcoma;
effect ... See more keywords
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Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00774
Abstract: Hypospadias and urethral stricture are common urological diseases which seriously affect voiding function and life quality of the patients, yet current clinical treatments often result in unsatisfactory clinical outcome with frequent complications. In vitro experiments…
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Keywords:
icg 001;
study;
functional urethra;
dog model ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14051281
Abstract: Simple Summary Colorectal cancer (CRC) is one of the most frequently diagnosed and lethal malignancies. The majority of CRC patients experience disease relapse after the primary curative treatment strategy of surgery followed by 5FU-based chemotherapy.…
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Keywords:
metformin icg;
crc;
icg 001;
cancer ... See more keywords
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Published in 2019 at "Annals of Dermatology"
DOI: 10.5021/ad.2019.31.6.631
Abstract: Background The canonical Wnt/β-catenin signaling pathway is a fundamental regulatory system involved in various biological events. ICG-001 selectively blocks the interaction of β-catenin with its transcriptional co-activator cyclic AMP response element-binding protein (CBP). Recent studies…
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Keywords:
catenin;
activator cyclic;
like dermatitis;
icg 001 ... See more keywords