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Published in 2022 at "Journal of pharmacological and toxicological methods"
DOI: 10.2139/ssrn.4119523
Abstract: ICH S7B recommends screening for hERG channel block using patch clamp recordings to assess a drug's proarrhythmic risk. Block of the hERG channel has been associated with clinical QTC prolongation as well as the rare,…
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Keywords:
herg external;
ich s7b;
external solution;