Immune checkpoint inhibitors and kidney disease
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000805
Abstract: Purpose of review Immune checkpoint inhibitors (ICIs) have changed the landscape of cancer treatment. However, use of ICIs can be limited by inflammatory toxicities referred to as immune-related adverse events (irAEs). ICI-associated acute kidney injury… read more here.
Keywords: ici associated; checkpoint inhibitors; immune checkpoint; associated aki ... See more keywords
Abstract 4358585: Hemodynamic Subtypes of Pulmonary Hypertension Based on Right Heart Catheterization Data Predict Outcomes in ICI-Associated Myocarditis
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4358585
Abstract: Background: Pulmonary hypertension (PH) is a known complication in patients with cancer, arising from both therapies and malignancies. Immune checkpoint inhibitor (ICI)-associated myocarditis has been linked to PH in case reports, but its impact on… read more here.
Keywords: pre capillary; post capillary; mmhg; ici associated ... See more keywords
Immune hemolytic anemia associated with the use of immune checkpoint inhibitors: a scoping review
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1586426
Abstract: Background Immune-hemolytic anemia (IHA) is a rare immune-related adverse event (irAE) in cancer patients treated with immune-checkpoint inhibitors (ICIs). Although several cases of ICI-associated IHA have been reported, few attempts have been made to collate… read more here.
Keywords: scoping review; ici associated; immune hemolytic; associated iha ... See more keywords
Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1556373
Abstract: Background Peripheral immune cells can predict responses to immune checkpoint inhibitor (ICI) therapy, but their relationship with early ICI-associated cardiovascular adverse events (CVAEs) is unclear. This study aimed to assess the predictive value of peripheral… read more here.
Keywords: immune checkpoint; cell; checkpoint inhibitor; associated cardiovascular ... See more keywords
Case Series of Steroid-Resistant Immune Checkpoint Inhibitor Associated Myocarditis: A Comparative Analysis of Corticosteroid and Tofacitinib Treatment
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.770631
Abstract: Background: Immune checkpoint inhibitor (ICI)–associated myocarditis is an uncommon and potentially fatal immune-related adverse event (irAE). Although corticosteroids are recommended as the first-line treatment by current guidelines, patients still have variable responses to it, and… read more here.
Keywords: analysis; ici associated; corticosteroid; treatment ... See more keywords
Pancreatic Adverse Events Associated With Immune Checkpoint Inhibitors: A Large-Scale Pharmacovigilance Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.817662
Abstract: Backgrounds: Immune checkpoint inhibitors (ICIs) are considered cornerstones of oncology treatment with durable anti-tumor efficacy, but the increasing use of ICIs is associated with the risk of developing immune-related adverse events (irAEs). Although ICI-associated pancreatic… read more here.
Keywords: pancreatic aes; adverse events; ici associated; ror025 ic025 ... See more keywords
Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.986357
Abstract: Introduction: With the widespread application of Immune checkpoint inhibitors (ICIs), it is important to explore the association between ICIs and cardiac arrhythmias and to characterize the clinical features of ICI-associated cardiac arrhythmias in real-world studies.… read more here.
Keywords: ici associated; checkpoint inhibitors; immune checkpoint; cardiac arrhythmias ... See more keywords
Sarcoid-like Granulomatosis Associated with Immune Checkpoint Inhibitors in Melanoma
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DOI: 10.3390/cancers14122937
Abstract: Simple Summary Granulomatosis is commonly observed in patients receiving immune checkpoint inhibitors (ICIs) for melanoma and other cancers. Recognizing this reaction early is critical to avoid confusing it with cancer progression. Our objectives were to… read more here.
Keywords: sarcoidosis; granulomatosis; ici associated; checkpoint inhibitors ... See more keywords
Fatal Myocarditis Following Adjuvant Immunotherapy: A Case Report and Literature Review
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms262311646
Abstract: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by enhancing the immune response against tumors. However, they can cause immune-related adverse events (irAEs), including rare but potentially fatal myocarditis. We describe a 71-year-old man with… read more here.
Keywords: fatal myocarditis; ici associated; literature; myocarditis following ... See more keywords
Immune Checkpoint Inhibitor-associated Pneumonitis: A Narrative Review
Sign Up to like & getrecommendations! Published in 2025 at "Western Journal of Emergency Medicine"
DOI: 10.5811/westjem.20305
Abstract: Immune checkpoint inhibitors (ICI), such as pembrolizumab, nivolumab, durvalumab and ipilimumab, have significantly enhanced survival rates for multiple cancer types such as non-small cell lung cancer, melanoma, Hodgkin lymphoma, and breast cancer, and they have… read more here.
Keywords: cancer; immune checkpoint; pneumonitis; ici associated ... See more keywords