Immune checkpoint inhibitors and kidney disease
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000805
Abstract: Purpose of review Immune checkpoint inhibitors (ICIs) have changed the landscape of cancer treatment. However, use of ICIs can be limited by inflammatory toxicities referred to as immune-related adverse events (irAEs). ICI-associated acute kidney injury… read more here.
Keywords: ici associated; checkpoint inhibitors; immune checkpoint; associated aki ... See more keywords
Case Series of Steroid-Resistant Immune Checkpoint Inhibitor Associated Myocarditis: A Comparative Analysis of Corticosteroid and Tofacitinib Treatment
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.770631
Abstract: Background: Immune checkpoint inhibitor (ICI)–associated myocarditis is an uncommon and potentially fatal immune-related adverse event (irAE). Although corticosteroids are recommended as the first-line treatment by current guidelines, patients still have variable responses to it, and… read more here.
Keywords: analysis; ici associated; corticosteroid; treatment ... See more keywords
Pancreatic Adverse Events Associated With Immune Checkpoint Inhibitors: A Large-Scale Pharmacovigilance Analysis
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DOI: 10.3389/fphar.2022.817662
Abstract: Backgrounds: Immune checkpoint inhibitors (ICIs) are considered cornerstones of oncology treatment with durable anti-tumor efficacy, but the increasing use of ICIs is associated with the risk of developing immune-related adverse events (irAEs). Although ICI-associated pancreatic… read more here.
Keywords: pancreatic aes; adverse events; ici associated; ror025 ic025 ... See more keywords
Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.986357
Abstract: Introduction: With the widespread application of Immune checkpoint inhibitors (ICIs), it is important to explore the association between ICIs and cardiac arrhythmias and to characterize the clinical features of ICI-associated cardiac arrhythmias in real-world studies.… read more here.
Keywords: ici associated; checkpoint inhibitors; immune checkpoint; cardiac arrhythmias ... See more keywords
Sarcoid-like Granulomatosis Associated with Immune Checkpoint Inhibitors in Melanoma
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DOI: 10.3390/cancers14122937
Abstract: Simple Summary Granulomatosis is commonly observed in patients receiving immune checkpoint inhibitors (ICIs) for melanoma and other cancers. Recognizing this reaction early is critical to avoid confusing it with cancer progression. Our objectives were to… read more here.
Keywords: sarcoidosis; granulomatosis; ici associated; checkpoint inhibitors ... See more keywords