Immune Checkpoint Inhibitors (ICIs)-Related Cardiotoxicity.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-41008-7_15
Abstract: The growing success of immune checkpoint inhibitors (ICIs) has led to effectively treating several types of cancers. Even though their use has been associated with the development of cardiac adverse effects, which may decrease the… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; related cardiotoxicity; icis related ... See more keywords
Protective Effect of Crocin on Immune Checkpoint Inhibitors-Related Myocarditis Through Inhibiting NLRP3 Mediated Pyroptosis in Cardiomyocytes via NF-κB Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s348464
Abstract: Purpose Immune checkpoint inhibitors (ICIs)-related myocarditis is now one of the most critical immune-related adverse effects (irAEs) in tumor immunotherapy, which has raised great concern in cardio-oncology. The pathogenesis involved in cardiac injury remains elusive.… read more here.
Keywords: myocarditis; related myocarditis; immune checkpoint; pyroptosis ... See more keywords