Investigation of ICOS, CD28 and CD80 polymorphisms with the risk of hepatocellular carcinoma: a case–control study in eastern Chinese population
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20181824
Abstract: Single nucleotide polymorphisms (SNPs) in immune related gene may influence the susceptibility of cancer. We selected inducible T cell costimulator (ICOS) rs4404254 T>C, rs10932029 T>C, CD28 rs3116496 T>C and CD80 rs7628626 C>A SNPs and assessed… read more here.
Keywords: hepatocellular carcinoma; hcc; icos cd28; risk ... See more keywords
Inducible T‐cell costimulator (ICOS) and CD28 polymorphisms possibly play a role in the pathogenesis of chronic autoreactive urticaria
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.13212
Abstract: Clinical experience emphasizes the coexistence of chronic spontaneous urticaria (CSU) and autoimmune disturbances. In chromosome 2q33‐34, there is a cluster of homologous genes that are considered promising candidate genes for susceptibility to autoimmune diseases. read more here.
Keywords: icos cd28; inducible cell; polymorphisms possibly; costimulator icos ... See more keywords
Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4+ T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.915963
Abstract: Costimulatory molecules of the CD28 family play a crucial role in the activation of immune responses in T lymphocytes, complementing and modulating signals originating from the T-cell receptor (TCR) complex. Although distinct functional roles have… read more here.
Keywords: icos cd28; cd28 costimulatory; cd4 cells; cd28 ... See more keywords