Herpes simplex virus diverts CIN85 endosomal cargo for exocytosis to evade antiviral responses: a novel role for the viral immediate-early protein ICP0
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DOI: 10.1128/mbio.02143-25
Abstract: ABSTRACT Endocytosis and exocytosis pathways are critical for the survival of the cells. Viruses often hijack these trafficking pathways to support cell entry, replication, and egress and to evade host antiviral responses. The infected cell… read more here.
Keywords: icp0; endocytosis; virus; protein ... See more keywords
A 77 Amino Acid Region in the N-Terminal Half of the HSV-1 E3 Ubiquitin Ligase ICP0 Contributes to Counteracting an Established Type 1 Interferon Response
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DOI: 10.1128/spectrum.00593-22
Abstract: Interferons (IFNs) are secreted cellular factors that are induced by viral infection and limit replication. HSV-1 is largely refractory to the antiviral effects of type 1 IFNs, which are synthesized shortly after viral infection, in… read more here.
Keywords: terminal half; region; hsv; ifn ... See more keywords