Selenothymidine protects against biochemical and behavioral alterations induced by ICV-STZ model of dementia in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.08.004
Abstract: The present study evaluated the neuroprotective effects of one selenium-containing AZT derivative compound (S1073) in memory and learning impairment caused by Intracerebroventricular-streptozotocin (ICV-STZ). ICV-STZ in mice causes impairment of energy metabolism with oxidative damage and… read more here.
Keywords: dementia; icv stz; stz; model ... See more keywords
Oral treatment with royal jelly improves memory and presents neuroprotective effects on icv-STZ rat model of sporadic Alzheimer's disease
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DOI: 10.1016/j.heliyon.2020.e03281
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive decline in cognitive function. Intracerebroventricular injection of streptozotocin (icv-STZ) has been used as an experimental model of Sporadic AD (SAD) in rodents and represents a… read more here.
Keywords: icv stz; alzheimer disease; model; royal jelly ... See more keywords
Clostridium butyricum improves cognitive dysfunction in ICV-STZ-induced Alzheimer’s disease mice via suppressing TLR4 signaling pathway through the gut-brain axis
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DOI: 10.1371/journal.pone.0286086
Abstract: In recent years, the relationship between gut-brain axis and Alzheimer’s disease (AD) attracted increasing attention. The aim of this study is to investigate the therapeutic effect of Clostridium butyricum (CB) on intraventricular injection of streptozotocin… read more here.
Keywords: icv stz; gut brain; mice;
Animal model of Alzheimer’s disease induced by streptozotocin: New insights about cholinergic pathway
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DOI: 10.2139/ssrn.4133018
Abstract: Alzheimer's disease (AD) presents multifactorial origin, and still presents several gaps regarding its development and progression. Disorders of the cholinergic system are well known to be involved in the pathogenesis of AD, characterized by increased… read more here.
Keywords: cholinergic system; alzheimer disease; animal model; model ... See more keywords