Abnormal regulation of miR-29b-ID1 signaling is involved in the process of decitabine resistance in leukemia cells
Sign Up to like & getrecommendations! Published in 2023 at "Cell Cycle"
DOI: 10.1080/15384101.2023.2200312
Abstract: ABSTRACT Decitabine (DAC) is an inhibitor of DNA methyltransferase used to treat leukemia, but primary or secondary resistance to DAC may develop during therapy. The mechanisms related to DAC resistance remain poorly understood. In this… read more here.
Keywords: mir 29b; id1; leukemia; expression ... See more keywords
Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noac141
Abstract: Abstract Background Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis and limited understanding of the mechanism behind tumor invasion. Previous reports demonstrate upregulation of the protein… read more here.
Keywords: id1; dmg; prenatal pontine; diffuse midline ... See more keywords
The miR-371∼373 Cluster Represses Colon Cancer Initiation and Metastatic Colonization by Inhibiting the TGFBR2/ID1 Signaling Axis.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-3003
Abstract: The vast majority of colorectal cancer-related deaths can be attributed to metastatic spreading of the disease. Therefore, deciphering molecular mechanisms of metastatic dissemination is a key prerequisite to improve future treatment options. With this aim,… read more here.
Keywords: mir 371; 373 cluster; id1; 371 373 ... See more keywords
Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.
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DOI: 10.1158/0008-5472.can-18-1479
Abstract: Because of the refractory nature of mutant KRAS lung adenocarcinoma (LUAD) to current therapies, identification of new molecular targets is essential. Genes with a prognostic role in mutant KRAS LUAD have proven to be potential… read more here.
Keywords: kras luad; metastasis; lung adenocarcinoma; inhibitor differentiation ... See more keywords
Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning
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DOI: 10.2337/db16-1079
Abstract: Obesity results from increased energy intake or defects in energy expenditure. Brown adipose tissue (BAT) is specialized for energy expenditure, a process called adaptive thermogenesis. Peroxisome proliferator–activated receptor γ coactivator 1α (PGC1α) controls BAT-mediated thermogenesis… read more here.
Keywords: id1 promotes; white adipose; id1; adipose tissue ... See more keywords