Lineage tracing reveals the dynamic contribution of Id2+ progenitor cells to branching morphogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2021.0135
Abstract: Branching morphogenesis is an important process in shaping the arborized structures of several organs. However, the driving force that directs this process from progenitor pools remains incompletely understood. In this lineage tracing study, we investigated… read more here.
Keywords: id2; cells branching; progenitor; branching morphogenesis ... See more keywords
Identification of prognostic and immunotherapy-related eRNA ID2-AS1 in bladder cancer
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029759
Abstract: AbstractEnhancer RNAs (eRNAs) can participate in enhancer regulation and target gene transcription, thus affecting the occurrence and development of tumors. In this study, we identified eRNAs closely related to bladder cancer (BLCA). Gene expression profiles… read more here.
Keywords: bladder cancer; id2 as1; expression; id2 ... See more keywords
ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abh0068
Abstract: Description ID2 reduces the interferon response to viral infections by inhibiting the activation of IRF3. ID2 interferes with IRF3 activation Inhibitor of DNA binding protein 2 (ID2) controls the development and differentiation of various immune… read more here.
Keywords: id2; infection; tbk1 ikk; irf3 ... See more keywords
Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5
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DOI: 10.1128/mcb.00250-17
Abstract: ABSTRACT The cellular components and function of the gastrointestinal epithelium exhibit distinct characteristics depending on the region, e.g., stomach or intestine. How these region-specific epithelial characteristics are generated during development remains poorly understood. Here, we… read more here.
Keywords: id2; determines intestinal; irx5; epithelium ... See more keywords
Id2 Represses Aldosterone-Stimulated Cardiac T-Type Calcium Channels Expression
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22073561
Abstract: Aldosterone excess is a cardiovascular risk factor. Aldosterone can directly stimulate an electrical remodeling of cardiomyocytes leading to cardiac arrhythmia and hypertrophy. L-type and T-type voltage-gated calcium (Ca2+) channels expression are increased by aldosterone in… read more here.
Keywords: type; channels expression; aldosterone stimulated; id2 ... See more keywords
Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5215
Abstract: Activin A (Act A) has been reported to promote oligodendrocyte progenitor cell (OPC) differentiation in vitro and improve neurological outcomes in adult mice. However, the roles and mechanisms of action of Act A in preterm… read more here.
Keywords: id2; act; brain injury; preterm brain ... See more keywords