Relationship Between Obesity and Intellectual/Developmental Disability in an Ohio Telepsychiatry Clinic: A Retrospective Review
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Autism and Developmental Disorders"
DOI: 10.1007/s10803-024-06432-0
Abstract: Co-occurring intellectual/developmental disability (IDD) and overweight/obesity (OW/OB) is an important consideration of IDD psychiatric care. The relationship between OW/OB and comorbid diagnoses of Autism Spectrum Disorder (ASD) and/or IDD remains inadequately described in existing literature.… read more here.
Keywords: relationship; obesity; intellectual developmental; retrospective review ... See more keywords
A population-based study identifies an association of THBS2 with intervertebral disc degeneration.
Sign Up to like & getrecommendations! Published in 2019 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2019.06.001
Abstract: OBJECTIVE To clarify the genetic mechanisms underlying intervertebral disc degeneration (IDD), we examined the associations between single-nucleotide polymorphisms (SNPs) and IDD in a general population in Japan. METHODS This was a cross-sectional study. In 1,605… read more here.
Keywords: age; disc degeneration; idd; intervertebral disc ... See more keywords
FokI as a genetic factor of intervertebral disc degeneration: A PRISMA-compliant systematic review of overlapping meta-analyses
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2018.09.028
Abstract: The association of FokI (rs2228570), a polymorphism of the vitamin D receptor gene, with intervertebral disc degeneration (IDD) has been investigated in a multitude of studies. However, conflicting results of these studies led to emergence… read more here.
Keywords: meta analyses; meta; association foki; idd ... See more keywords
Characterization of An Extensive Interface on Vitronectin for Binding to PAI-1: Adoption of Structure in an Intrinsically Disordered Region.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00605
Abstract: Small-angle neutron scattering (SANS) measurements were pursued to study human vitronectin, a protein found in tissues and the circulation that regulates cell adhesion/migration and proteolytic cascades that govern hemostasis and pericellular proteolysis. Many of these… read more here.
Keywords: vitronectin; pai; binding pai; idd ... See more keywords
CXCL14 drives age-related intervertebral disc degeneration via NF-κB pathway activation in a multiomic study
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-10998-9
Abstract: Intervertebral disc degeneration (IDD), a common cause of chronic low back pain, strongly impacts daily life. Although previous studies have identified certain biomarkers indicating IDD, comprehensive analyses that integrate transcriptomic and proteomic data to elucidate… read more here.
Keywords: disc degeneration; intervertebral disc; transcriptomic proteomic; age related ... See more keywords
Research progress in decellularized extracellular matrix hydrogels for intervertebral disc degeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01862d
Abstract: As one of the most common clinical disorders, low back pain (LBP) influences patient quality of life and causes substantial social and economic burdens. Many factors can result in LBP, the most common of which… read more here.
Keywords: disc degeneration; intervertebral disc; idd; research ... See more keywords
Comprehensive analysis of abnormal methylation modification differential expression mRNAs between low-grade and high-grade intervertebral disc degeneration and its correlation with immune cells
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Medicine"
DOI: 10.1080/07853890.2024.2357742
Abstract: Abstract Background Intervertebral disc degeneration (IDD) is an important cause of low back pain. The aim of this study is to identify the potential molecular mechanism of abnormal methylation-modified DNA in the progression of IDD,… read more here.
Keywords: methylation; correlation; analysis; grade ... See more keywords
MicroRNA-129-5p affects immune privilege and apoptosis of nucleus pulposus cells via regulating FADD in intervertebral disc degeneration
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1732515
Abstract: ABSTRACT Literatures indicate that microRNA-129-5p (miR-129-5p) or Fas-associated death domain (FADD) is related to intervertebral disc degeneration (IDD), but the effect of miR-129-5p/FADD axis on IDD is not studied. The study aimed to investigate whether… read more here.
Keywords: apoptosis; mir 129; idd; nucleus pulposus ... See more keywords
The Role of Type I Diabetes in Intervertebral Disc Degeneration.
Sign Up to like & getrecommendations! Published in 2019 at "Spine"
DOI: 10.1097/brs.0000000000003054
Abstract: STUDY DESIGN An experimental laboratory study. OBJECTIVE To investigate the pathogenesis of intervertebral disc degeneration (IDD) in a murine model of type 1 diabetes mellitus (DM), namely non-obese diabetic (NOD) mouse. SUMMARY OF BACKGROUND DATA… read more here.
Keywords: idd; type diabetes; intervertebral disc; disc degeneration ... See more keywords
Causal relationship between systemic circulatory inflammatory regulators and intervertebral disc degeneration: A bidirectional 2-sample Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000039521
Abstract: In the context of the development of intervertebral disc degeneration (IDD), inflammatory mediators play a pivotal role. Nevertheless, due to the influence of the inflammatory microenvironment, the causal relationship between specific inflammatory mediators and the… read more here.
Keywords: idd; disc degeneration; causal relationship; inflammatory ... See more keywords
Low bone mineral density as a causal risk factor for cervical and thoracolumbar intervertebral disc degeneration: A Mendelian randomization analysis
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000045874
Abstract: Bone mineral density (BMD) is a key indicator of osteoporosis, which may influence the development of intervertebral disc degeneration (IDD). However, the causal relationship and underlying signaling pathways between BMD and IDD remain unclear. Therefore,… read more here.
Keywords: analysis; risk; bmd; causal ... See more keywords