HBV Antigen‐Guided Switching Strategy From Nucleos(t)ide Analogue to Interferon: Avoid Virologic Breakthrough and Improve Functional Cure
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DOI: 10.1002/jmv.70021
Abstract: Little is known for factors associated with virologic breakthrough (VBT) after switching from nucleos(t)ide analogue (NA) to pegylated interferon alpha (Peg‐IFN‐α) for patients with chronic hepatitis B (CHB). Eighty patients who received 48‐week Peg‐IFN‐ɑ and… read more here.
Keywords: hbv; peg ifn; hbcrag log10u; nucleos ide ... See more keywords
Negative HBcAg in immunohistochemistry assay of liver biopsy is a predictive factor for the treatment of patients with nucleos(t)ide analogue therapy
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DOI: 10.1111/jcmm.13444
Abstract: The hepatitis B core antigen (HBcAg) is an important target for antiviral response in chronic hepatitis B (CHB) patients. However, the correlation between HBcAg in the hepatocyte nucleus and nucleos(t)ide analogue (NA) therapeutic response is… read more here.
Keywords: week; nucleos ide; ide analogue; hbcag group ... See more keywords
TDF Monotherapy Is Effective Regardless of Prior Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patients in China
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DOI: 10.1155/2017/2463197
Abstract: Background/Aims Many patients had to transfer to tenofovir disoproxil fumarate (TDF) if there is other nucleos(t)ide analogue (NA) resistance. We aimed to investigate antiviral effects of TDF monotherapy between NA-naive and NA-experienced chronic hepatitis B… read more here.
Keywords: nucleos ide; tdf monotherapy; ide analogue; dna ... See more keywords
Retracted: Finite versus Indefinite Nucleos(t)ide Analogue Therapy of Patients with Chronic Hepatitis B Exhibiting Negative HBsAg Levels after Treatment
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DOI: 10.1155/2024/9894173
Abstract: [This retracts the article DOI: 10.1155/2022/6069781.]. read more here.
Keywords: retracted finite; nucleos ide; indefinite nucleos; ide analogue ... See more keywords
Is it possible to stop nucleos(t)ide analogue treatment in chronic hepatitis B patients?
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DOI: 10.3748/wjg.v24.i17.1825
Abstract: Chronic hepatitis B (CHB) remains a challenging global health problem, with nearly one million related deaths per year. Nucleos(t)ide analogue (NA) treatment suppresses viral replication but does not provide complete cure of the hepatitis B… read more here.
Keywords: nucleos ide; ide analogue; hepatitis; treatment ... See more keywords