Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice
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DOI: 10.1002/jbt.22876
Abstract: Shc expression rises in human nonalcoholic steatohepatitis (NASH) livers, and Shc‐deficient mice are protected from NASH—thus Shc inhibition could be a novel therapeutic strategy for NASH. Idebenone was recently identified as the first small‐molecule Shc… read more here.
Keywords: fibrosis; shc expression; idebenone ameliorates; shc inhibitor ... See more keywords