Allogreffe de cellules souches hématopoïétiques dans la drépanocytose de l’enfant et de l’adulte : indications et modalités
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin Du Cancer"
DOI: 10.1016/j.bulcan.2020.06.003
Abstract: Sickle cell disease is associated with severe complications and early mortality in adults. In children, hematopoietic stem cell transplant from HLA-identical sibling can stop the progression of the disease and leads to more than 95%… read more here.
Keywords: identical sibling; disease; hla identical; cell disease ... See more keywords
Individual HLAs influence immunological events in allogeneic stem cell transplantation from HLA-identical sibling donors
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DOI: 10.1038/s41409-020-01070-3
Abstract: In allogeneic hematopoietic stem cell transplantation (allo-HSCT), the effects of patient and donor human leukocyte antigen (HLA) matching status on graft-versus-host disease (GVHD) have been extensively elucidated, but the effects of specific HLAs on acute… read more here.
Keywords: acute gvhd; identical sibling; cell transplantation; stem cell ... See more keywords
Transplant results in adults with Fanconi anaemia
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DOI: 10.1111/bjh.15006
Abstract: The outcomes of adult patients transplanted for Fanconi anaemia (FA) have not been well described. We retrospectively analysed 199 adult patients with FA transplanted between 1991 and 2014. Patients were a median of 16 years… read more here.
Keywords: transplant results; identical sibling; fanconi anaemia; results adults ... See more keywords
Comparison of outcomes in hematological malignancies treated with haploidentical or HLA-identical sibling hematopoietic stem cell transplantation following myeloablative conditioning: A meta-analysis
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DOI: 10.1371/journal.pone.0191955
Abstract: Purpose Haploidentical and human leukocyte antigen (HLA)-identical sibling hematopoietic stem transplantation are two main ways used in allogeneic hematopoietic stem cell transplantation (allo-HSCT). In recent years, remarkable progress has been made in haploidentical allo-HSCT (HID-SCT),… read more here.
Keywords: isd sct; identical sibling; hla identical; transplantation ... See more keywords
Comparable long-term outcomes between upfront haploidentical and identical sibling donor transplant in aplastic anemia: a national registry-based study
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DOI: 10.3324/haematol.2022.280758
Abstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains a curative option for severe aplastic anemia (SAA), and transplantation from identical sibling donors (ISD) has been recommended as a first-line treatment. Haploidentical donor (HID) transplantation for SAA… read more here.
Keywords: donor; identical sibling; sct; isd sct ... See more keywords
Immune tolerance induced by hematopoietic stem cell infusion after HLA identical sibling kidney transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.995243
Abstract: After the first attempt to induce operational tolerance, it has taken decades to implement it in clinical practice. Recipients with Human leukocyte antigen (HLA) identical sibling donors were enrolled. Hematopoietic stem cells (HSCs) infusion was… read more here.
Keywords: hla identical; identical sibling; transplantation; tolerance ... See more keywords
LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1066393
Abstract: Introduction The association of polymorphisms in molecules involved in the immune response (checkpoint inhibitors) with the clinical outcome after allogeneic transplantation (alloHSCT) has been described. Lymphocyte Activation 3 (LAG3) is a surface protein that plays… read more here.
Keywords: hla identical; donor; identical sibling; lag3 genotype ... See more keywords