Identification of acrylamide-based covalent inhibitors of SARS-CoV-2 (SCoV-2) Nsp15 using high-throughput screening and machine learning
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DOI: 10.1039/d4ra06955b
Abstract: Non-structural protein 15 (Nsp15) is a SARS-CoV-2 (SCoV-2) endoribonuclease and is a promising target for drug development because of its essential role in evading the host immune system. However, developing inhibitors against Nsp15 has been… read more here.
Keywords: sars cov; identification acrylamide; cov scov; covalent inhibitors ... See more keywords