Isolation and identification of anti-proliferative peptides from Spirulina platensis using three-step hydrolysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.7815
Abstract: BACKGROUND Spirulina platensis is an excellent source of proteins (>60%) that can be hydrolyzed into bioactive peptides. RESULTS In this study, whole proteins of Spirulina platensis were extracted and hydrolyzed using three gastrointestinal endopeptidases (pepsin,… read more here.
Keywords: platensis; using three; spirulina platensis; identification anti ... See more keywords
Identification of anti-diabetes peptides from Spirulina platensis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.03.024
Abstract: Abstract In this study, ultrasound coupled with subcritical water (USW) technology was employed to extract S. platensis protein, and its inhibitory effect on three enzymes (α-amylase, α-glucosidase and dipeptidyl peptidase-4 (DPP-IV)) was evaluated. Subsequently, using… read more here.
Keywords: diabetes peptides; platensis; anti diabetes; peptides spirulina ... See more keywords
Efficient Identification of Anti-SARS-CoV-2 Compounds Using Chemical Structure- and Biological Activity-Based Modeling
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.1c01372
Abstract: Identification of anti-SARS-CoV-2 compounds through traditional high-throughput screening (HTS) assays is limited by high costs and low hit rates. To address these challenges, we developed machine learning models to identify compounds acting via inhibition of… read more here.
Keywords: anti sars; cov compounds; identification anti; sars cov ... See more keywords
Screening and identification of an anti-PD-1 nanobody with antitumor activity
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DOI: 10.1042/bsr20221546
Abstract: Abstract Blocking of programmed death protein 1 (PD-1) or its ligand PD-L1 with corresponding antibody to enhance T-cell response and mediate antitumor activity has been successfully applied in clinical practice. Several immune checkpoint inhibitors including… read more here.
Keywords: antitumor; antitumor activity; anti nanobody; identification anti ... See more keywords
Identification of the anti‐mycobacterial functional properties of piperidinol derivatives
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DOI: 10.1111/bph.13744
Abstract: Tuberculosis (TB) remains a major global health threat and is now the leading cause of death from a single infectious agent worldwide. The current TB drug regimen is inadequate, and new anti‐tubercular agents are urgently… read more here.
Keywords: functional properties; anti mycobacterial; properties piperidinol; identification anti ... See more keywords
Aristolochia trilobata: Identification of the Anti-Inflammatory and Antinociceptive Effects
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DOI: 10.3390/biomedicines8050111
Abstract: Aristolochia trilobata, popularly known as “mil-homens,” is widely used for treatment of stomach aches, colic, asthma, pulmonary diseases, diabetes, and skin affection. We evaluated the antinociceptive and anti-inflammatory activities of the essential oil (EO) and… read more here.
Keywords: anti inflammatory; aristolochia trilobata; antinociceptive effects; inflammatory antinociceptive ... See more keywords
Identification of Anti-TNFα VNAR Single Domain Antibodies from Whitespotted Bambooshark (Chiloscyllium plagiosum)
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DOI: 10.3390/md20050307
Abstract: Tumor necrosis factor α (TNFα), an important clinical testing factor and drug target, can trigger serious autoimmune diseases and inflammation. Thus, the TNFα antibodies have great potential application in diagnostics and therapy fields. The variable… read more here.
Keywords: anti tnf; tnf; vnar; identification anti ... See more keywords