Identification of 2-Benzylidene-tetralone Derivatives as Highly Potent and Reversible Firefly Luciferase Inhibitors.
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DOI: 10.1021/acsmedchemlett.1c00671
Abstract: The extensive applications of Firefly luciferase (Fluc) in numerous biological, biomedical, and clinical investigations rendered an urgent need for efficient and biocompatible Fluc inhibitors for the construction of novel assay platforms. Herein we describe the… read more here.
Keywords: firefly luciferase; tetralone derivatives; benzylidene tetralone; derivatives highly ... See more keywords