Identification and Biological Activity of NFAT-133 Congeners from Streptomyces pactum.
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DOI: 10.1021/acs.jnatprod.1c00152
Abstract: The soil bacterium Streptomyces pactum ATCC 27456 produces a number of polyketide natural products. Among them is NFAT-133, an inhibitor of the nuclear factor of activated T cells (NFAT) that suppresses interleukin-2 (IL-2) expression and… read more here.
Keywords: biological activity; atcc 27456; nfat 133; identification biological ... See more keywords
Semi-automated identification of biological control agent using artificial intelligence
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DOI: 10.1038/s41598-020-71798-x
Abstract: The accurate identification of biological control agents is necessary for monitoring and preventing contamination in integrated pest management (IPM); however, this is difficult for non-taxonomists to achieve in the field. Many machine learning techniques have… read more here.
Keywords: control; automated identification; identification biological; control agent ... See more keywords
Identification of biological pathway and process regulators using sparse partial least squares and triple-gene mutual interaction
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DOI: 10.1038/s41598-021-92610-4
Abstract: Identification of biological process- and pathway-specific regulators is essential for advancing our understanding of regulation and formation of various phenotypic and complex traits. In this study, we applied two methods, triple-gene mutual interaction (TGMI) and… read more here.
Keywords: mutual interaction; gene mutual; identification biological; pathway ... See more keywords
Assessment of BOLD and GenBank – Their accuracy and reliability for the identification of biological materials
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DOI: 10.1371/journal.pone.0217084
Abstract: Taxonomic identification of biological materials can be achieved through DNA barcoding, where an unknown “barcode” sequence is compared to a reference database. In many disciplines, obtaining accurate taxonomic identifications can be imperative (e.g., evolutionary biology,… read more here.
Keywords: bold genbank; barcode; identification biological; accuracy reliability ... See more keywords
Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors
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DOI: 10.3390/ph15070855
Abstract: NAPRT, the rate-limiting enzyme of the Preiss–Handler NAD biosynthetic pathway, has emerged as a key biomarker for the clinical success of NAMPT inhibitors in cancer treatment. Previous studies found that high protein levels of NAPRT… read more here.
Keywords: biological characterization; structure; naprt inhibitors; based identification ... See more keywords
Text mining for identification of biological entities related to antibiotic resistant organisms
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DOI: 10.7717/peerj.13351
Abstract: Antimicrobial resistance is a significant public health problem worldwide. In recent years, the scientific community has been intensifying efforts to combat this problem; many experiments have been developed, and many articles are published in this… read more here.
Keywords: mining identification; scientific articles; text mining; identification biological ... See more keywords