Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8967-6_10
Abstract: In this protocol, pooled sgRNA libraries targeting thousands of genes are computationally designed, generated using microarray-based synthesis techniques, and packaged into lentiviral particles. Target cells of interest are transduced with the lentiviral sgRNA pools to… read more here.
Keywords: identification cancer; genome wide; cas9; wide crispr ... See more keywords
Identification of cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers
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DOI: 10.1093/carcin/bgx122
Abstract: We provide evidence of how RAD51AP1 can be of importance as potential biomarker since it is overexpressed in both tissue and peripheral blood of ovarian and lung cancer patients. Silencing of the gene can also… read more here.
Keywords: identification cancer; gene; ovarian lung; rad51ap1 ... See more keywords
Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-16-0873
Abstract: Actin filaments, with their associated tropomyosin polymers, and microtubules are dynamic cytoskeletal systems regulating numerous cell functions. While antimicrotubule drugs are well-established, antiactin drugs have been more elusive. We previously targeted actin in cancer cells… read more here.
Keywords: antimicrotubule agents; identification cancer; cancer cells; cancer ... See more keywords
Identification of Cancer Survivors Living with PTSD on Social Media
Sign Up to like & getrecommendations! Published in 2019 at "Studies in health technology and informatics"
DOI: 10.3233/shti190488
Abstract: The trauma of cancer often leaves survivors with PTSD. Tweets posted on Twitter usually reflect the users' psychological state, which is convenient for data collection. However, Twitter also contains a mix of noisy and genuine… read more here.
Keywords: cancer survivors; identification cancer; living ptsd; cancer ... See more keywords