Identification and characterization of a novel glutaminase inhibitor.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13319
Abstract: In humans, there are two forms of glutaminase (GLS), designated GLS1 and GLS2. These enzymes catalyze the conversion of glutamine to glutamate. GLS1 exists as two isozymes: kidney glutaminase (KGA) and glutaminase C (GAC). Several… read more here.
Keywords: characterization novel; inhibitor; glutaminase; novel glutaminase ... See more keywords
Identification and characterization of a novel esterase from Thauera sp.
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1659
Abstract: A novel esterase gene TLip was identified from the strain Thauera sp. and expressed at high levels in Escherichia coli. The TLip protein shared the highest identity (48%) to esterase TesA from Pseudomonas aeruginosa when… read more here.
Keywords: characterization novel; tlip; novel esterase; thauera ... See more keywords
Identification and characterization of metamorphic proteins: Current and future perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Biopolymers"
DOI: 10.1002/bip.23473
Abstract: Proteins that can reversibly alternate between distinctly different folds under native conditions are described as being metamorphic. The “metamorphome” is the collection of all metamorphic proteins in the proteome, but it remains unknown the extent… read more here.
Keywords: current future; characterization metamorphic; future perspectives; metamorphic proteins ... See more keywords
Update on Metabolism of Abemaciclib: In Silico, In vitro and In vivo Metabolite Identification and Characterization using High Resolution Mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2725
Abstract: Abemaciclib is approved by US Food and Drug Administration in 2015 to have an advanced treatment for metastatic breast cancer. Identification and characterization of limited numbers of abemaciclib metabolites have been reported in the literature.… read more here.
Keywords: high resolution; vitro vivo; mass; using high ... See more keywords
Identification and characterization of design fires and particle emissions to be used in performance‐based fire design of nuclear facilities
Sign Up to like & getrecommendations! Published in 2020 at "Fire and Materials"
DOI: 10.1002/fam.2881
Abstract: CERN operates one of the most complex particle accelerator facilities in the world. Several different hazards, including fires, are present and need to be investigated and reduced to a tolerable level. Toward this goal, CERN… read more here.
Keywords: particle emissions; nuclear facilities; fire; identification characterization ... See more keywords
Identification and characterization of metformin on peptidomic profiling in human visceral adipocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26347
Abstract: To gain insight into the effect of metformin on losing weight from peptidomic perspective and to screen potential active peptides for reducing fat lipid deposition. After determining the proper concentration of metformin on human primary… read more here.
Keywords: metformin; characterization metformin; metformin peptidomic; peptidomic profiling ... See more keywords
Molecular identification and characterization of measles virus genotypes circulating in Afghanistan, 2008–2018
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27707
Abstract: The measles virus (MV) remains a leading cause of morbidity and mortality in children under 5 years of age. Molecular identification of circulating wild‐type MV) strains is a vital component of the measles elimination program.… read more here.
Keywords: measles virus; identification; afghanistan 2008; molecular identification ... See more keywords
Identification and characterization of the novel bioactive compounds from microalgae and cyanobacteria for pharmaceutical and nutraceutical applications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.202100477
Abstract: Microalgae and cyanobacteria (blue‐green algae) are used as food by humans. They have gained a lot of attention in recent years because of their potential applications in biotechnology. Microalgae and cyanobacteria are good sources of… read more here.
Keywords: characterization novel; bioactive compounds; nutraceutical applications; pharmaceutical nutraceutical ... See more keywords
Identification and characterization of novel ligase I inhibitors
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DOI: 10.1002/mc.22516
Abstract: The terminal step of ligation of single and/or double‐strand breaks during physiological processes such as DNA replication, repair and recombination requires participation of DNA ligases in all mammals. DNA Ligase I has been well characterised… read more here.
Keywords: dna; dna ligase; cancer cells; ligase inhibitors ... See more keywords
Identification and Characterization of Stem Cells in Oral Cancer.
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DOI: 10.1007/7651_2018_184
Abstract: Cancer stem cells (CSCs) are a subpopulation of cells within a heterogeneous tumor that have enhanced biologic properties such as increased capacity for self-renewal, increased tumorigenicity, enhanced differentiation capacity, and resistance to chemo- and radiotherapies.… read more here.
Keywords: oral cancer; cancer; stem cells; characterization stem ... See more keywords
Identification and Characterization of Reproductive Mutations in Arabidopsis.
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DOI: 10.1007/978-1-0716-0880-7_18
Abstract: Mutations in numerous genes affect reproduction in Arabidopsis leading to sterility and abortion of seed development, respectively. These include mutations in regulators of reproductive development and fertilization, but also in house-keeping genes lacking mutant phenotypes… read more here.
Keywords: seed; characterization reproductive; mutations arabidopsis; reproductive mutations ... See more keywords