The Identification of GPR52 Agonist HTL0041178, a Potential Therapy for Schizophrenia and Related Psychiatric Disorders.
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DOI: 10.1021/acsmedchemlett.3c00052
Abstract: HTL0041178 (1), a potent GPR52 agonist with a promising pharmacokinetic profile and exhibiting oral activity in preclinical models, has been identified. This molecule was the outcome of a judicious molecular property-based optimization approach, focusing on… read more here.
Keywords: gpr52 agonist; agonist htl0041178; identification gpr52; htl0041178 potential ... See more keywords