Integrated Covalent Drug Design Workflow Using Site Identification by Ligand Competitive Saturation.
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DOI: 10.1021/acs.jctc.3c00232
Abstract: Covalent drug design is an important component in drug discovery. Traditional drugs interact with their target in a reversible equilibrium, while irreversible covalent drugs increase the drug-target interaction duration by forming a covalent bond with… read more here.
Keywords: covalent drug; drug design; site identification; identification ligand ... See more keywords