Identification of Linomide Derivatives as Potential Anticancer Therapeutics using Molecular Docking Studies
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DOI: 10.3389/fphar.2022.892914
Abstract: 12 analogs bearing a structural similarity to Linomide, a bonafide anticancer agent were synthesized wherein cyclization of substituted dianilides rendered 4-hydroxyquinolin-2(1H)-ones that were subjected to a Mannich reaction to yield 4-hydroxy-3-(substituted-1-ylmethyl) quinolin-2(1H)-one analogs. Characterization was… read more here.
Keywords: anticancer therapeutics; identification linomide; docking studies; anticancer ... See more keywords