Identification of α‐Mangostin as an Agonist of Human STING
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DOI: 10.1002/cmdc.201800481
Abstract: The xanthone derivate 5′,6′‐dimethylxanthenone‐4‐acetic acid (DMXAA, also known as ASA404 or vadimezan) is a potent agonist of murine STING (stimulator of interferon genes), but cannot activate human STING. Herein we report that α‐mangostin, which bears… read more here.
Keywords: mangostin agonist; human sting; identification mangostin; agonist human ... See more keywords