Identification of a new Z‐DNA inducer using SYBR green 1 as a DNA conformation sensor
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13513
Abstract: Z‐DNA, which is left‐handed double‐stranded DNA, is involved in various cellular processes. However, its biological roles have not been fully evaluated due to the lack of tools available that can control the precise conformational change… read more here.
Keywords: identification new; dna; new dna; dna inducer ... See more keywords
Rapid Identification of New Psychoactive Substances in Letters by LA-APCI-MS.
Sign Up to like & getrecommendations! Published in 2025 at "Drug testing and analysis"
DOI: 10.1002/dta.70003
Abstract: New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled into prisons via infused mail. Consumption of those substances by inmates in prisons is associated with increased aggression, violence, and organized crime.… read more here.
Keywords: rapid identification; new psychoactive; psychoactive substances; mail ... See more keywords
Identification of a new mutation in the ACTL9 gene in men with unexplained infertility
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2448
Abstract: Infertility is defined as the failure to achieve pregnancy after one year of unprotected intercourse within a marital relationship. Approximately 10%–15% of couples worldwide experience infertility issues, with nearly half of these cases attributed to… read more here.
Keywords: infertility; men unexplained; actl9 gene; unexplained infertility ... See more keywords
Identification of a new potyvirus isolated from Angelica keiskei
Sign Up to like & getrecommendations! Published in 2021 at "Journal of General Plant Pathology"
DOI: 10.1007/s10327-020-00978-4
Abstract: A potyvirus with the proposed name ashitaba mosaic virus was detected in ashitaba [Angelica keiskei (Miq.)] plants exhibiting mosaic and vein clearing in Japan. The host range of the virus includes species from three families,… read more here.
Keywords: potyvirus; new potyvirus; virus; identification new ... See more keywords
Immunosenescence in multiple sclerosis: The identification of new therapeutic targets.
Sign Up to like & getrecommendations! Published in 2021 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2021.102893
Abstract: The number of elderly multiple sclerosis (MS) patients is growing, mainly due to the increase in the life expectancy of the general population and the availability of effective disease-modifying treatments. However, current treatments reduce the… read more here.
Keywords: sclerosis; identification new; sclerosis identification; immunosenescence multiple ... See more keywords
Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.09.001
Abstract: Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a crucial role in cancer angiogenesis. In the current study, a series of novel pyrrolo[2,3-d]pyrimidine based-compounds was designed and synthesized as VEGFR-2 inhibitors, in accordance to the structure… read more here.
Keywords: kinase inhibitors; pyrrolo pyrimidines; identification new; kinase ... See more keywords
Identification of a new natural biflavonoids against breast cancer cells induced ferroptosis via the mitochondrial pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104744
Abstract: Breast cancer is one of the major malignant tumors in females, and currently, recurrence and metastasis are the main obstacles preventing effective breast cancer treatment. Biflavonoids of secondary metabolites from plants are excellent anticancer agents… read more here.
Keywords: identification new; breast; breast cancer; ferroptosis ... See more keywords
Isolation and identification of a new Colletotrichum species causing anthracnose of Astragalus membranaceus
Sign Up to like & getrecommendations! Published in 2021 at "Crop Protection"
DOI: 10.1016/j.cropro.2020.105470
Abstract: Abstract Anthracnose is regarded as a destructive disease in agriculture. In this study, the disease symptoms of black dots on Astragalus membranaceus, similar to those of anthracnose reported previously, were investigated at Weiyuan, Gansu province,… read more here.
Keywords: astragalus membranaceus; isolation identification; identification new; colletotrichum species ... See more keywords
Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112355
Abstract: In this work, unique flavopiridol analogs bearing thiosugars, amino acids and heterocyclic moieties tethered to the flavopiridol via thioether and amine bonds mainly on its C ring have been prepared. The analogs bearing thioether-benzimidazoles as… read more here.
Keywords: identification new; cytotoxic; flavopiridol like; series flavopiridol ... See more keywords
Identification of new bioactive peptides from Kefir milk through proteopeptidomics: Bioprospection of antihypertensive molecules.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.01.010
Abstract: Kefir, a probiotic beverage prepared from fermented milk, has been associated with antihypertensive activity. However, the bioactive molecules responsible for this activity still remain unclear. Therefore, in this study we aim to evaluate the mechanisms… read more here.
Keywords: milk; peptides kefir; identification new; new bioactive ... See more keywords
Challenges in the identification of new thermolabile psychoactive substances: The 25I-NBOH case.
Sign Up to like & getrecommendations! Published in 2020 at "Forensic science international"
DOI: 10.1016/j.forsciint.2020.110306
Abstract: The continuous emergence of NPS over the last years poses a series of novel challenges for forensic analysts. Most of those new compounds are synthesized with minimal chemical modifications to the structure of already known… read more here.
Keywords: new thermolabile; challenges identification; identification new; analysis ... See more keywords