Articles with "identification parp12" as a keyword



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Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.847499

Abstract: Poly [adenosine diphosphate (ADP)-ribose] polymerases (PARPs) are members of a family of 17 enzymes that performs several fundamental cellular processes. Aberrant activity (mutation) in PARP12 has been linked to various diseases including inflammation, cardiovascular disease,… read more here.

Keywords: inhibitors virtual; identification parp12; virtual screening; molecular dynamics ... See more keywords