Articles with "identification piperazinylmethyl" as a keyword



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Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights

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Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2022.2062337

Abstract: Abstract In the current work, a hybridisation strategy was adopted between the privileged building blocks, benzofuran and piperazine, with the aim of designing novel CDK2 type II inhibitors. The hybrid structures were linked to different… read more here.

Keywords: cell; identification piperazinylmethyl; cdk2; benzofuran derivatives ... See more keywords