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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9055-9_11
Abstract: Phosphorylation, the process by which a phosphate group is attached to a preexisting protein, is an evolutionarily and metabolically cheap way to change the protein's surface and properties. It is presumably for that reason that…
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Keywords:
protein;
identification protein;
phosphorylation sites;
protein phosphorylation ... See more keywords
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Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107770
Abstract: G-protein-gated inwardly rectifying K+ (GIRK) channels are essential effectors of inhibitory neurotransmission in the brain. GIRK channels have been implicated in diseases with abnormal neuronal excitability, including epilepsy and addiction. GIRK channels are tetramers composed…
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Keywords:
identification protein;
independent activator;
protein independent;
girk channels ... See more keywords
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Published in 2019 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.10.046
Abstract: Protein S-sulfenylation is an essential post-translational modification (PTM) that provides critical information to understand molecular mechanisms of cell signaling transduction, stress response and regulation of cellular functions. Recent advancements in computational methods have contributed towards…
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Keywords:
identification protein;
protein sulfenylation;
sulfpred model;
sulfenylation ... See more keywords
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Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00968
Abstract: Alternative splicing can lead to distinct protein isoforms. These can have different functions in specific cells and tissues or in different developmental stages. In this study, we explored whether transcripts assembled from long read, nanopore-based,…
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Keywords:
rna seq;
read rna;
protein isoforms;
identification protein ... See more keywords
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Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad175
Abstract: MOTIVATION Identifying and prioritizing disease-related proteins is an important scientific problem to develop proper treatments. Network science has become an important discipline to prioritize such proteins. Multiple sclerosis (MS), an autoimmune disease for which there…
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Keywords:
interaction;
sclerosis;
identification protein;
immune cells ... See more keywords
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Published in 2020 at "BMC Microbiology"
DOI: 10.1186/s12866-020-01904-6
Abstract: Escherichia coli always plays an important role in microbial research, and it has been a benchmark model for the study of molecular mechanisms of microorganisms. Molecular complexes, operons, and functional modules are valuable molecular functional…
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Keywords:
protein;
identification protein;
functional modules;
ppi networks ... See more keywords
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Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.9414
Abstract: Myocardial infarction (MI) is a leading cause of mortality and disability worldwide. Determination of the molecular mechanisms underlying the disease is crucial for identifying possible therapeutic targets and designing effective treatments. On the basis that…
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Keywords:
protein;
identification protein;
myocardial infarction;
bioinformatics approach ... See more keywords