Identification of a second Klotho interaction site in the C terminus of FGF23.
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DOI: 10.1016/j.celrep.2020.108665
Abstract: FGF23 interacts with a FGFR/KL-receptor complex to propagate cellular signaling, where its C-terminal C26 peptide is critical for engaging the co-receptor KL. We identify a distinct peptide sequence C28 residing in the FGF23 C terminus… read more here.
Keywords: terminus; terminus fgf23; identification second; site ... See more keywords