Identification and targeting of regulators of SARS-CoV-2–host interactions in the airway epithelium
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.adu2079
Abstract: The impact of SARS-CoV-2 in the lung has been extensively studied, yet the molecular regulators of host-cell programs hijacked by the virus in distinct human airway epithelial cell populations remain poorly understood. Some of the… read more here.
Keywords: sars cov; targeting regulators; host; host interactions ... See more keywords
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2018-08-870089
Abstract: Aberrant activation of mTOR signaling in acute myeloid leukemia (AML) results in a survival advantage that promotes the malignant phenotype. To improve our understanding of factors that contribute to mammalian target of rapamycin (mTOR) signaling… read more here.
Keywords: myeloid leukemia; cdk9; identification targeting; mtor ... See more keywords
Identification and Targeting of Mutant Neoantigens in Multiple Myeloma Treatment
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DOI: 10.3390/curroncol30050348
Abstract: Multiple myeloma (MM) is malignant disease characterized by the clonal proliferation of plasma cells in the bone marrow, leading to anemia, immunosuppression, and other symptoms, that is generally hard to treat. In MM, the immune… read more here.
Keywords: targeting mutant; identification targeting; neoantigens multiple; mutant neoantigens ... See more keywords