Identification of thiazolo[5,4-d]pyrimidine derivatives as potent antiproliferative agents through the drug repurposing strategy.
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DOI: 10.1016/j.ejmech.2017.04.056
Abstract: A series of thiazolo[5,4-d]pyrimidine derivatives were synthesized and evaluated for their antiproliferative activities on three cancer cell lines. The structure-activity relationship studies were conducted through the variation in the three regions of the thiazolo-pyrimidine core.… read more here.
Keywords: thiazolo pyrimidine; potent antiproliferative; identification thiazolo; pyrimidine derivatives ... See more keywords