Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses
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DOI: 10.1021/acs.jmedchem.2c00697
Abstract: From a designed library of indolyl pyrimidinamines, we identified a highly potent and cell-active chemical probe (17) that inhibits phosphatidylinositol-3-phosphate 5-kinase (PIKfyve). Comprehensive evaluation of inhibitor selectivity confirmed that this PIKfyve probe demonstrates excellent kinome-wide… read more here.
Keywords: roles pikfyve; chemical probe; lifecycle coronaviruses; identification utilization ... See more keywords
Identification and utilization of a new Bacillus amyloliquefaciens XY-1 against Fusarium head blight
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DOI: 10.3389/fpls.2022.1055213
Abstract: Fusarium head blight (FHB) is a global wheat grain disease caused by Fusarium graminearum. Biological control of FHB is considered to be an alternative disease management strategy that is environmentally benign, durable, and compatible with… read more here.
Keywords: bacillus amyloliquefaciens; head blight; fusarium head; identification utilization ... See more keywords