Identification and validation of circulating exosomes‐based liquid biopsy for esophageal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2224
Abstract: Early detection of esophageal squamous cell carcinoma (ESCC) recurrence is a key element for follow‐up care and surveillance. The aim of this study is to detect the level of circulating exosomes (CEs) in ESCC patient… read more here.
Keywords: identification validation; circulating exosomes; exosomes based; based liquid ... See more keywords
Identification and Validation of Driver Kinases from Next-Generation Sequencing Data.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7154-1_12
Abstract: It is well appreciated that activating mutations in kinase genes result in kinome reprogramming that leads to altered downstream signaling networks that drive tumor progression. Indeed small-molecule inhibition of activated kinases has heralded the wave… read more here.
Keywords: validation driver; next generation; generation sequencing; identification validation ... See more keywords
Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2017.12.006
Abstract: The 3' untranslated region (UTR) of mRNAs is the primary regulatory region that mediates post-transcriptional control by microRNAs and RNA-binding proteins in the cytoplasm. Aside from individual sequence-specific binding and regulation, examples of interaction between… read more here.
Keywords: wide identification; identification validation; hur; validation interactions ... See more keywords
Identification and validation of a prognostic proteomic signature for cervical cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2019.08.021
Abstract: OBJECTIVE To date, The Cancer Genome Atlas (TCGA) has provided the most extensive molecular characterization of invasive cervical cancer (ICC). Analysis of reverse phase protein array (RPPA) data from TCGA samples showed that cervical cancers… read more here.
Keywords: identification validation; survival outcome; cervical cancer; icc ... See more keywords
Identification and validation of reference genes for RT-qPCR analysis in Sclerodermus guani (Hymenoptera: Bethylidae).
Sign Up to like & getrecommendations! Published in 2024 at "Bulletin of entomological research"
DOI: 10.1017/s0007485324000427
Abstract: Gene expression studies in organisms are often conducted using reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR), and the accuracy of RT-qPCR results relies on the stability of reference genes. We examined ten candidate reference genes in… read more here.
Keywords: body part; identification validation; reference; sclerodermus guani ... See more keywords
Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01693
Abstract: Interleukin-2 (IL2) is a pro-inflammatory cytokine that plays a crucial role in immunity, which is increasingly being used for therapeutic applications. There is growing interest in developing IL2-based therapeutics which do not interact with the… read more here.
Keywords: new interleukin; identification validation; chemistry; dna encoded ... See more keywords
Identification and validation of ecto-5' nucleotidase as an immunotherapeutic target in multiple myeloma.
Sign Up to like & getrecommendations! Published in 2022 at "Blood cancer journal"
DOI: 10.1038/s41408-022-00635-3
Abstract: Interaction of plasmacytoid dendritic cells (pDCs) with multiple myeloma (MM) cells, T- or NK-effector cells in the bone marrow (BM) microenvironment induces tumor cell growth, as well as inhibits innate and adaptive immune responses. Defining… read more here.
Keywords: nucleotidase immunotherapeutic; validation ecto; multiple myeloma; identification validation ... See more keywords
Identification and validation of a miRNA-based prognostic signature for cervical cancer through an integrated bioinformatics approach
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-79337-4
Abstract: Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical cancer. However, the mechanisms that affect the prognosis of cancer are… read more here.
Keywords: identification validation; bioinformatics approach; cervical cancer; integrated bioinformatics ... See more keywords
Identification and validation of LY6H and GRM3 as candidate biomarkers for Glioma-related epilepsy
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-97333-4
Abstract: Gliomas are the most common primary tumors of the central nervous system, with epilepsy serving as a frequent clinical manifestation. Glioma-related epilepsy (GRE) significantly affects patients’ quality of life and prognosis. In this study, we… read more here.
Keywords: related epilepsy; identification validation; glioma related; ly6h grm3 ... See more keywords
Bioinformatics identification and validation of aging-related molecular subtype and prognostic signature in sarcoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer investigation"
DOI: 10.1080/07357907.2023.2209638
Abstract: Aging could regulate many biological processes in malignancies by regulating cell senescence. Consensus cluster analysis was conducted to differentiate TCGA sarcoma cases. LASSO cox regression analysis was performed to construct an aging-related prognostic signature. We… read more here.
Keywords: sarcoma; prognostic signature; identification validation; aging related ... See more keywords
RETRACTED ARTICLE: Integrated bioinformatics approach for the identification and validation of novel biomarkers in ACC progression and prognosis
Sign Up to like & getrecommendations! Published in 2025 at "Biomarkers"
DOI: 10.1080/1354750x.2025.2489453
Abstract: We, the Editor and Publisher of Biomarkers, have retracted the following article: Tuli, T. R., Mia, M., & Habib, A. (2025). Integrated bioinformatics approach for the identification and validation of novel biomarkers in ACC progression… read more here.
Keywords: identification validation; integrated bioinformatics; bioinformatics approach; validation novel ... See more keywords