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   Articles with "identification validation" as a keyword



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Identification and validation of circulating exosomes‐based liquid biopsy for esophageal cancer

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recommendations! Published in 2019 at "Cancer Medicine"

DOI: 10.1002/cam4.2224

Abstract: Early detection of esophageal squamous cell carcinoma (ESCC) recurrence is a key element for follow‐up care and surveillance. The aim of this study is to detect the level of circulating exosomes (CEs) in ESCC patient… read more here.

Keywords: identification validation; circulating exosomes; exosomes based; based liquid ... See more keywords
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Identification and Validation of Driver Kinases from Next-Generation Sequencing Data.

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recommendations! Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7154-1_12

Abstract: It is well appreciated that activating mutations in kinase genes result in kinome reprogramming that leads to altered downstream signaling networks that drive tumor progression. Indeed small-molecule inhibition of activated kinases has heralded the wave… read more here.

Keywords: validation driver; next generation; generation sequencing; identification validation ... See more keywords
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Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets.

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recommendations! Published in 2018 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2017.12.006

Abstract: The 3' untranslated region (UTR) of mRNAs is the primary regulatory region that mediates post-transcriptional control by microRNAs and RNA-binding proteins in the cytoplasm. Aside from individual sequence-specific binding and regulation, examples of interaction between… read more here.

Keywords: wide identification; identification validation; hur; validation interactions ... See more keywords
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Identification and validation of a prognostic proteomic signature for cervical cancer.

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recommendations! Published in 2019 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2019.08.021

Abstract: OBJECTIVE To date, The Cancer Genome Atlas (TCGA) has provided the most extensive molecular characterization of invasive cervical cancer (ICC). Analysis of reverse phase protein array (RPPA) data from TCGA samples showed that cervical cancers… read more here.

Keywords: identification validation; survival outcome; cervical cancer; icc ... See more keywords
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Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries.

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recommendations! Published in 2021 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.1c01693

Abstract: Interleukin-2 (IL2) is a pro-inflammatory cytokine that plays a crucial role in immunity, which is increasingly being used for therapeutic applications. There is growing interest in developing IL2-based therapeutics which do not interact with the… read more here.

Keywords: new interleukin; identification validation; chemistry; dna encoded ... See more keywords
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Identification and validation of ecto-5' nucleotidase as an immunotherapeutic target in multiple myeloma.

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recommendations! Published in 2022 at "Blood cancer journal"

DOI: 10.1038/s41408-022-00635-3

Abstract: Interaction of plasmacytoid dendritic cells (pDCs) with multiple myeloma (MM) cells, T- or NK-effector cells in the bone marrow (BM) microenvironment induces tumor cell growth, as well as inhibits innate and adaptive immune responses. Defining… read more here.

Keywords: nucleotidase immunotherapeutic; validation ecto; multiple myeloma; identification validation ... See more keywords
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Identification and validation of a miRNA-based prognostic signature for cervical cancer through an integrated bioinformatics approach

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-79337-4

Abstract: Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical cancer. However, the mechanisms that affect the prognosis of cancer are… read more here.

Keywords: identification validation; bioinformatics approach; cervical cancer; integrated bioinformatics ... See more keywords
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Bioinformatics identification and validation of aging-related molecular subtype and prognostic signature in sarcoma.

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recommendations! Published in 2023 at "Cancer investigation"

DOI: 10.1080/07357907.2023.2209638

Abstract: Aging could regulate many biological processes in malignancies by regulating cell senescence. Consensus cluster analysis was conducted to differentiate TCGA sarcoma cases. LASSO cox regression analysis was performed to construct an aging-related prognostic signature. We… read more here.

Keywords: sarcoma; prognostic signature; identification validation; aging related ... See more keywords
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Identification and validation of an angiogenesis-related signature associated with preeclampsia by bioinformatic analysis

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recommendations! Published in 2023 at "Medicine"

DOI: 10.1097/md.0000000000032741

Abstract: Preeclampsia (PE) is a pregnancy disorder with high morbidity and mortality rates for both mothers and newborns. This study explores potential diagnostic indicators of PE. We downloaded the messenger ribonucleic acid profiles of the GSE75010… read more here.

Keywords: angiogenesis related; validation angiogenesis; signature; validation ... See more keywords
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Identification and validation of amino acid‐based mild exfoliating agents through a de novo screening method

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recommendations! Published in 2019 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.12871

Abstract: Due to internal or external factors, the desquamation (turnover) rate of the stratum corneum slows down, resulting in skin problems. Therefore, adjusting the exfoliation rate through cosmetics is an important issue. read more here.

Keywords: validation amino; acid based; amino acid; identification validation ... See more keywords
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Identification and Validation of 7-lncRNA Signature of Epigenetic Disorders by Comprehensive Epigenetic Analysis

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recommendations! Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/5118444

Abstract: The survival rate of patients with lung adenocarcinoma (LUAD) is low. This study analyzed the correlation between the expression of long noncoding RNA (lncRNA) and epigenetic alterations along with the investigation of the prognostic value… read more here.

Keywords: lncrnas identified; as1; analysis; validation lncrna ... See more keywords