Identification, in vitro evaluation and modeling studies of the constituents from the roots of Arnebia euchroma for antitumor activity and STAT3 inhibition.
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DOI: 10.1016/j.bioorg.2020.103655
Abstract: Phytochemical investigation of the roots of Arnebia euchroma led to the isolation of a new dimeric naphthoquinone, shikometabolin H (1), a new meroterpeniod, epoxyarnebinol (5) and a new ring A-seco hopane triterpenoid, 2, 3-secodiplopterol dioic… read more here.
Keywords: identification vitro; vitro evaluation; stat3; arnebia euchroma ... See more keywords
Identification of In Vitro Metabolites of Synthetic Phenolic Antioxidants BHT, BHA, and TBHQ by LC-HRMS/MS
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DOI: 10.3390/ijms21249525
Abstract: Butylated hydroxytoluene (BHT) and its analogs, butylated hydroxyanisole (BHA) and tert-butyl-hydroquinone (TBHQ), are widely used synthetic preservatives to inhibit lipid oxidation in the food, cosmetic and pharmaceutical industries. Despite their widespread use, little is known… read more here.
Keywords: synthetic phenolic; metabolites synthetic; identification vitro; tbhq ... See more keywords
In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents
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DOI: 10.3390/ijms24010725
Abstract: Different molecular mechanisms contribute to the development of multidrug resistance in cancer, including increased drug efflux, enhanced cellular repair mechanisms and alterations of drug metabolism or drug targets. ABCG2 is a member of the ATP-binding… read more here.
Keywords: new abcg2; identification vitro; silico identification; vitro evaluation ... See more keywords
Species Identification and In Vitro Antifungal Susceptibility of Paecilomyces/Purpureocillium Species Isolated from Clinical Respiratory Samples: A Multicenter Study
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DOI: 10.3390/jof8070684
Abstract: Paecilomyces spp. are emerging fungal pathogens, where Paecilomyces lilacinus and Paecilomyces variotii are the most reported species. Taxonomic and phylogenetic revisions in this genus have shown that P. variotii represents a species complex, whereas P.… read more here.
Keywords: paecilomyces spp; species identification; antifungal susceptibility; purpureocillium ... See more keywords