Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity
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DOI: 10.1038/s41388-020-01592-6
Abstract: Cancer cell expression of PD-L1 leads to T cells exhaustion by transducing co-inhibitory signal, and further understanding the regulation of PD-L1 in cancer cells may provide additional therapeutic strategies. Here by drug repurposing screen, we… read more here.
Keywords: degradation; identifies amlodipine; screen identifies; repurposing screen ... See more keywords