Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases
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DOI: 10.1038/s41598-020-69431-y
Abstract: Bacteria are known to evade β-lactam antibiotic action by producing β-lactamases (BLs), including carbapenemases, which are able to hydrolyze nearly all available β-lactams. The production of BLs represents one of the best known and most… read more here.
Keywords: virtual screening; screening identifies; clinically relevant; identifies broad ... See more keywords