Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.
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DOI: 10.1038/nchembio.2458
Abstract: Enhancing production of the anti-inflammatory cytokine interleukin-10 (IL-10) is a promising strategy to suppress pathogenic inflammation. To identify new mechanisms regulating IL-10 production, we conducted a phenotypic screen for small molecules that enhance IL-10 secretion… read more here.
Keywords: identify cdk8; small molecule; cdk8 cdk19; cdk8 ... See more keywords