High-Throughput Screening to Identify Inhibitors of SSB-Protein Interactions.
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DOI: 10.1007/978-1-0716-1290-3_7
Abstract: The bacterial single-stranded DNA-binding protein (SSB) uses an acidic C-terminal tail to interact with over a dozen proteins, acting as a genome maintenance hub. These SSB-protein interactions are essential, as mutations to the C-terminal tail… read more here.
Keywords: protein interactions; inhibitors ssb; high throughput; identify inhibitors ... See more keywords
Repurposing screens of FDA-approved drugs identify 29 inhibitors of SARS-CoV-2.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.2009.09009
Abstract: COVID-19, caused by a novel coronavirus, SARS-CoV-2, has spread globally and caused serious social and economic problems. The WHO has declared this outbreak a pandemic. Currently, there are no approved vaccines or antiviral drugs. Drugs… read more here.
Keywords: inhibitors sars; approved drugs; identify inhibitors; sars cov ... See more keywords