Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model
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DOI: 10.1021/acschemneuro.1c00804
Abstract: Lysosomes are intracellular organelles responsible for the degradation of diverse macromolecules in a cell. A highly acidic pH is required for the optimal functioning of lysosomal enzymes. Loss of lysosomal intralumenal acidity can disrupt cellular… read more here.
Keywords: cell; lysosomal modulators; phenotypic screening; screening using ... See more keywords