Ischemia/reperfusion‐associated tubular cells injury in renal transplantation: Can metabolomics inform about mechanisms and help identify new therapeutic targets?
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2017.12.032
Abstract: Graphical abstract Figure. No caption available. &NA; Tubular cells are central targets of ischemia‐reperfusion (I/R) injury in kidney transplantation. Inflammation and metabolic disturbances occurring within these cells are deleterious by themselves but also favor secondary… read more here.
Keywords: tubular cells; transplantation; identify new; ischemia reperfusion ... See more keywords
Scaffold-Hopping Approach To Identify New Chemotypes of Dimpropyridaz.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00636
Abstract: Dimpropyridaz is a pyrazole carboxamide insecticide with a novel mode of action, currently under worldwide development by BASF, providing excellent activity against sucking pests. A series of dimpropyridaz analogues were designed to investigate the impact… read more here.
Keywords: chemotypes dimpropyridaz; approach identify; new chemotypes; identify new ... See more keywords
Combinatorial Biomaterials Discovery Strategy to Identify New Macromolecular Cryoprotectants
Sign Up to like & getrecommendations! Published in 2020 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.0c00044
Abstract: Cryoprotective agents (CPAs) are typically solvents or small molecules, but there is a need for innovative CPAs to reduce toxicity and increase cell yield, for the banking and transport of cells. Here we use a… read more here.
Keywords: macromolecular cryoprotectants; strategy identify; identify new; discovery strategy ... See more keywords
Scanning the medical phenome to identify new diagnoses after recovery from COVID-19 in a US cohort
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocac159
Abstract: Abstract Objective COVID-19 survivors are at risk for long-term health effects, but assessing the sequelae of COVID-19 at large scales is challenging. High-throughput methods to efficiently identify new medical problems arising after acute medical events… read more here.
Keywords: covid survivors; identify new; temporal informed; cohort ... See more keywords
The Quest to Identify a New Virus Disease of Sunflower from Nebraska.
Sign Up to like & getrecommendations! Published in 2022 at "Plant disease"
DOI: 10.1094/pdis-11-21-2402-fe
Abstract: Between 2010 and 2018, sunflower plants exhibiting virus-like symptoms, including stunting, mottling, and chlorotic ringspots on leaves, were observed from commercial fields and research plots from four sites within three distinct counties of western Nebraska… read more here.
Keywords: new virus; disease; virus disease; quest identify ... See more keywords
Computational strategies to identify new drug candidates against neuroinflammation.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220208095122
Abstract: The even more increasing application of computational approaches in these last decades has deeply modified the process of discovery and commercialization of new therapeutic entities. This is especially true in the field of neuroinflammation, in… read more here.
Keywords: identify new; neuroinflammation; computational strategies; new drug ... See more keywords
Analysis of Spatiotemporal Urine Protein Dynamics to Identify New Biomarkers for Sepsis-Induced Acute Kidney Injury
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00139
Abstract: Acute kidney injury (AKI) is a frequent complication of sepsis and contributes to increased mortality. Discovery of reliable biomarkers could enable identification of individuals with high AKI risk as well as early AKI detection and… read more here.
Keywords: sepsis; kidney injury; acute kidney; identify new ... See more keywords
A High-Throughput Screening Approach to Identify New Active and Long-Term Stable Catalysts for Total Oxidation of Methane from Gas-Fueled Lean–Burn Engines
Sign Up to like & getrecommendations! Published in 2020 at "Catalysts"
DOI: 10.3390/catal10020159
Abstract: A unique high-throughput approach to identify new catalysts for total oxidation of methane from the exhaust gas of biogas-operated lean-burn engines is presented. The approach consists of three steps: (1) A primary screening using emission-corrected… read more here.
Keywords: gas; methane; approach identify; identify new ... See more keywords