Drug repurposing using computational methods to identify therapeutic options for COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes and Metabolic Disorders"
DOI: 10.1007/s40200-020-00546-9
Abstract: Purpose Recently, the world has been dealing with a new type of coronavirus called COVID-19 that in terms of symptoms is similar to the SARS coronavirus. Unfortunately, researchers could not find a registered therapy to… read more here.
Keywords: virtual screening; therapeutic options; drug repurposing; identify therapeutic ... See more keywords
An In-Silico Approach to Identify Therapeutic Target and Markers Associated with Diabetic Nephropathy.
Sign Up to like & getrecommendations! Published in 2022 at "Current diabetes reviews"
DOI: 10.2174/1573399819666220610191935
Abstract: BACKGROUND Renal disease in T2DM could arise independent of hyperglycemia, aka non diabetic kidney disease. Their prevalence ranges from 33%to72.5% among T2DM patients. Specific molecular signatures that distinguish Diabetic Nephropathy from NDKD (FSGS) in T2DM… read more here.
Keywords: approach identify; identify therapeutic; silico approach; analysis ... See more keywords
Proteomic Analyses Identify Therapeutic Targets in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.814120
Abstract: Hepatocellular carcinoma (HCC) is the fourth cause of cancer-related mortality worldwide. While many targeted therapies have been developed, the majority of HCC tumors do not harbor clinically actionable mutations. Protein-level aberrations, especially those not evident… read more here.
Keywords: hepatocellular carcinoma; proteomic analyses; identify therapeutic; targets hepatocellular ... See more keywords