iN6-Methyl (5-step): Identifying RNA N6-methyladenosine sites using deep learning mode via Chou's 5-step rules and Chou's general PseKNC
Sign Up to like & getrecommendations! Published in 2019 at "Chemometrics and Intelligent Laboratory Systems"
DOI: 10.1016/j.chemolab.2019.103811
Abstract: Abstract N6-methyladenosine (m6A) is an RNA methylation modification and it is involved in various biological progresses such as translation, alternative splicing, degradation, stability, etc. Therefore, it is highly recommended to develop computational models for detecting… read more here.
Keywords: methyladenosine; step identifying; in6 methyl; identifying rna ... See more keywords
Screening strategies for identifying RNA- and ribonucleoprotein-targeted compounds.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2021.06.001
Abstract: The past few years have witnessed important breakthroughs in the identification of compounds that specifically bind and regulate RNAs and in optimizing them for therapeutic use. Here, we review successful and unsuccessful approaches in screening… read more here.
Keywords: strategies identifying; rna; ribonucleoprotein targeted; rna ribonucleoprotein ... See more keywords