Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.07.013
Abstract: Cancer elimination in humans can be achieved with immunotherapy that relies on T lymphocyte-mediated recognition of tumor antigens. Several types of these antigens have been recognized based on their cellular origins and expression patterns, while… read more here.
Keywords: immunotherapy; tumor antigens; identifying targeting; human tumor ... See more keywords
Identifying and targeting angiogenesis-related microRNAs in ovarian cancer
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DOI: 10.1038/s41388-019-0862-y
Abstract: Current anti-angiogenic therapy for cancer is based mainly on inhibition of the vascular endothelial growth factor pathway. However, due to the transient and only modest benefit from such therapy, additional approaches are needed. Deregulation of… read more here.
Keywords: angiogenesis; targeting angiogenesis; identifying targeting; cancer ... See more keywords
Identifying and targeting the Achilles heel of a recalcitrant cancer
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abj6946
Abstract: Targeting replication stress response proteins in small cell lung cancer activates the innate immune cGAS-STING pathway leading to augmentation of immunotherapy’s antitumor response. Targeting replication stress response proteins in small cell lung cancer activates the… read more here.
Keywords: response; heel recalcitrant; identifying targeting; cancer ... See more keywords