A Fast and Simple Method for Detecting Identity by Descent Segments in Large-Scale Data.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2020.02.010
Abstract: Segments of identity by descent (IBD) are used in many genetic analyses. We present a method for detecting identical-by-descent haplotype segments in phased genotype data. Our method, called hap-IBD, combines a compressed representation of haplotype… read more here.
Keywords: method detecting; identity descent; hap ibd; descent ... See more keywords
Population-Specific Recombination Maps from Segments of Identity by Descent.
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DOI: 10.1016/j.ajhg.2020.05.016
Abstract: Recombination rates vary significantly across the genome, and estimates of recombination rates are needed for downstream analyses such as haplotype phasing and genotype imputation. Existing methods for recombination rate estimation are limited by insufficient amounts… read more here.
Keywords: recombination rates; identity descent; population; segments identity ... See more keywords
Distinguishing pedigree relationships via multi-way identity by descent sharing and sex-specific genetic maps.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2020.12.004
Abstract: The proportion of samples with one or more close relatives in a genetic dataset increases rapidly with sample size, necessitating relatedness modeling and enabling pedigree-based analyses. Despite this, relatives are generally unreported and current inference… read more here.
Keywords: specific genetic; identity descent; sex specific; genetic maps ... See more keywords
A clue to the etiology of disorders of sex development from identity-by-descent analysis in dogs with cryptic relatedness.
Sign Up to like & getrecommendations! Published in 2022 at "Animal genetics"
DOI: 10.1111/age.13276
Abstract: Disorders of sex development (DSDs) are discrepancies between sex chromosomes and phenotypical sex. Quite common forms of DSD in canine populations include testicular and ovotesticular XX DSDs with a normal set of sex chromosomes. The… read more here.
Keywords: descent analysis; french bulldogs; sex development; etiology ... See more keywords
Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007279
Abstract: Identification of genomic regions that are identical by descent (IBD) has proven useful for human genetic studies where analyses have led to the discovery of familial relatedness and fine-mapping of disease critical regions. Unfortunately however,… read more here.
Keywords: identity descent; analysis; selection; population ... See more keywords